BWPG in Precision Medicine
In the News....
Articles by or about our staff:
Enabling a Precision Medicine Program at a community cancer hospital
On being a Molecular Pathologist
Precision medicine vs. Evidence based Medicine
Mapping the Future of Cancer Treatment (page 15 of Journal)
Personalized Medicine and the Novel Variant: The case for Predictive Modeling
What is unique about precision Medicine?
Cancer is generally considered a GENETIC disease. This does not imply heredity in most cases, but that genes that drive tightly-controlled cellular processes are altered, leading to uncontrolled cellular proliferation (i.e., cancer).
Next-Generation Sequencing (NGS) allows for massively parallel sequencing of many genomic loci concurrently. This allows us to see “under the hood” of the tumor, and identify what cellular processes have gone awry in this tumor. Knowing these processes is beneficial, because targeting these altered pathways gives us the best opportunity to stop the aberrant pathways and thus stop the malignant processes.